Myocardial Infarction (Heart Attack)

 

Myocardial Infarction (Heart Attack)

 

Introduction:

A magnificent organ, the human heart circulates blood throughout the body, carrying oxygen and nutrients that are necessary for life. However, a myocardial infarction, also referred to as a heart attack, is one of the most serious disorders that can affect the heart. A heart attack happens when the blood flow to a portion of the heart is cut off, causing the heart muscle tissue to get damaged or even die. We will examine myocardial infarction's definition, causes, types, phases, symptoms, diagnostic standards, inquiries, and treatment alternatives in this blog.

Definition:

Myocardial infarction refers to the blockage of blood flow to a particular area of the heart muscle. The lack of blood supply prevents oxygen and nutrients from reaching the affected area, leading to tissue damage or necrosis.

Causes of Myocardial Infarction:

The development of a blood clot within a coronary artery, which provides blood to the heart muscle, is the most frequent cause of myocardial infarction. Atherosclerosis, a disorder marked by the accumulation of fatty deposits (plaque) within the arteries, is the most common cause of this clot, known as a cardiac thrombus. The plaque may burst, resulting in the development of a blood clot that restricts blood flow.

Heart attacks can also be brought on by coronary artery spasm, which causes the arteries to temporarily narrow and restrict blood flow, and less frequently by embolism (blockage brought on by a clot or piece of debris coming from another region of the body).

Types of Myocardial Infarction:

There are two main types of myocardial infarction:

  1. ST-segment elevation myocardial infarction (STEMI): This type of heart attack happens when a coronary artery is completely blocked, depriving a sizeable amount of the heart muscle of blood flow.
  2. Non-ST-segment elevation myocardial infarction (NSTEMI): In this type, a coronary artery is partially blocked, resulting in a less severe but still considerable reduction in the amount of blood flowing to the heart..

Stages of Myocardial Infarction:

The following stages are generally experienced during a heart attack:

  • Stage I: Ischemia: blocked coronary arteries that reduce blood flow to the heart muscle.
  • Stage II: Injury: The cells of the heart muscle are damaged by the absence of blood supply.
  • Stage III: Infarction: Complete blood flow restriction causes the damaged cells in the heart muscle to die permanently.

Signs & Symptoms of Myocardial Infarction:

The signs and symptoms of a heart attack can vary but often include:

  • Chest pain or discomfort (often described as pressure, squeezing, or tightness).
  • Pain radiating to the left arm, shoulder, jaw, neck, or back.
  • Shortness of breath.
  • Nausea, vomiting, or indigestion-like symptoms.
  • Dizziness or lightheadedness.
  • Cold sweats.
  • Fatigue or weakness.

Diagnostic Criteria of Myocardial Infarction:

Healthcare professionals take into account a number of factors to diagnose the heart attack, including:

  • Medical history and physical examination.
  • Electrocardiogram (ECG) to find heart electrical activity irregularities.
  • Blood tests, for evaluating heart muscle injury, cardiac biomarkers (troponin levels).
  • Imaging tests like echocardiography or coronary angiography to evaluate heart function and blood flow.

Investigations of Myocardial Infarction:

Further investigations may be necessary to determine the extent of the heart attack and the underlying cause. These can include:

  • Stress testing to assess heart health while exercising.
  • Holter monitoring to evaluate cardiac rhythm throughout the course of 24 to 48 hours.
  • Cardiac CT or MRI scans to capture accurate images of the blood vessels and heart.
  • Coronary angiography to see if there are any coronary artery blockages.

Treatment Options of Myocardial Infarction:

The goal of a heart attack treatment is to stop further complications and restore blood flow to the affected area. Typical interventions comprise:

  1. Medications: To dissolve clots, alleviate pain, and stop additional clotting, medications such as aspirin, nitroglycerin, and others that are antiplatelet and anticoagulant are given.
  2. Percutaneous coronary intervention (PCI): For this treatment, a catheter with a balloon or stent is inserted to unblock the coronary artery and allow blood flow.
  3. Coronary artery bypass grafting (CABG): In severe circumstances, bypass surgery can be necessary in order to open up new blood vessels around blocked arteries.
  4. Lifestyle changes: A balanced diet, regular exercise, quitting up smoking, and stress management are all components of a heart-healthy lifestyle that can help avoid future heart issues.

Preventions of Myocardial Infarction (Heart Attack)

In order to lower the risk of myocardial infarction or heart attack, prevention is essential. The following are some crucial tactics and lifestyle changes that can help prevent a heart attack:

  1. Healthy Diet: To keep a heart-healthy, balanced diet that includes:

  • Plenty of fruits and vegetables.
  • Whole grains.
  • Lean proteins, such as fish, poultry, and legumes.
  • Limited intake of saturated and trans fats, cholesterol, and sodium.
  • Avoiding processed and fried foods.

  1. Regular Exercise: Regularly move your body for at least 75 minutes of severe aerobic exercise or 150 minutes of moderate aerobic exercise per week. Include weight training workouts at least twice a week as well.
  2. Maintain a Healthy Weight: Aim to reach and maintain a healthy weight because carrying extra pounds, especially around the waist, raises the chance of developing heart disease. Even a tiny amount of weight loss can significantly improve cardiovascular health.
  3. Quit Smoking: Smoking harms blood arteries, decreases the amount of oxygen delivered to the heart, and raises the danger of blood clots. One of the best methods to lower your risk of heart attacks is to stop smoking. If necessary, get assistance from medical specialists or smoking cessation programmes.
  4. Limit Alcohol Consumption: Excessive consumption in alcohol can raise blood pressure and cause weight gain. It is recommended to moderately limit or completely avoid alcohol consumption.
  5. Manage Stress: Heart disease can be exacerbated by ongoing stress. Find healthy coping mechanisms for stress, such as routine exercise, restorative practices (such as deep breathing, yoga, and meditation), spending time with loved ones, and pursuing interests.
  6. Control Blood Pressure: Heart attacks are far more likely when blood pressure is high. Regularly check your blood pressure and work with your doctor to control it with lifestyle changes and, if required, medication.
  7. Manage Diabetes: Controlling blood sugar levels with diet, exercise, medication, and routine monitoring is crucial if you have diabetes. Diabetes that is not properly controlled raises the possibility of cardiovascular problems.
  8. Regular Health Check-ups: Regular medical checkups enable the early identification and control of heart disease risk factors. Monitor your cholesterol, blood sugar, and cardiovascular health generally.
  9. Medications: To control some risk factors for heart disease, medical experts occasionally prescribe pharmaceuticals like statins, antiplatelet agents, or blood pressure meds. Adhere to your doctor's advice and take your meds as directed.

Remember, in order to lower the risk of a heart attack, preventive is essential. You can greatly enhance your cardiovascular health and general well-being by adopting a healthy lifestyle and successfully controlling risk factors. Consult your healthcare practitioner for personalised recommendations and direction catered to your unique circumstances.

Conclusion:

Heart attack, also known as myocardial infarction, is a dangerous disease that needs immediate medical intervention. The likelihood of survival and risk of consequences can be significantly increased by recognizing the symptoms and getting immediate medical attention. It is possible to lessen the effects of heart attacks and improve cardiovascular health thanks to advancements in medical interventions and a focus on preventive measures.

Disclaimer: This blog is simply meant to provide information; it shouldn't be used to replace consultation with a doctor. For a diagnosis and available treatments, always seek the advice of a trained healthcare professional.

 

Dr.Muhammad Arsalan Khan
MBBS, DHHM, MSc (D & E)
CCD-BMJ-AKU-RCP (London)

Dilated Cardiomyopathy (DCM)

 

Dilated Cardiomyopathy (DCM)

Introduction:

The disorder known as dilated cardiomyopathy (DCM), which can be fatal, impairs the heart's ability to pump blood effectively. It is characterised by the left ventricle of the heart enlarging and weakening, which lowers its ability to pump blood. This article will discuss the definition, causes, kinds, stages, symptoms, diagnostic standards, tests, and available treatments for dilated cardiomyopathy.

Definition:

Dilated Cardiomyopathy is a form of heart muscle disease where the chambers of the heart become enlarged and weakened, resulting in poor blood circulation throughout the body. As the heart muscle stretches and becomes thinner, it becomes less efficient in pumping blood, leading to symptoms and potential complications.

Causes:

Many times, the precise cause of dilated cardiomyopathy is unknown. The growth of it, however, can be influenced by a number of circumstances and situations, like as:

  1. Genetic factors: Certain gene mutations that are passed down via families can cause hereditary Dilated Cardiomyopathy.
  2. Viral infections: Dilated Cardiomyopathy can be brought on by some viral infections, like myocarditis (heart muscle inflammation).
  3. Alcohol and substance abuse: Dilated Cardiomyopathy can be brought on by some viral infections, like myocarditis (heart muscle inflammation).
  4. Certain medications: Dilated Cardiomyopathy may result from the long-term use of various medications, including some antipsychotics and chemotherapeutic treatments.
  5. Autoimmune diseases: Dilated cardiomyopathy can be brought on by illnesses including lupus, sarcoidosis, or rheumatoid arthritis.
  6. Nutritional deficiencies: Dilated Cardiomyopathy can result from inadequate intake of vital nutrients like thiamine (vitamin B1).

Types of Dilated Cardiomyopathy:

Based on its source or accompanying disorders, dilated cardiomyopathy can be divided into several types, including:

  1. Idiopathic Dilated Cardiomyopathy: A considerable portion of cases have an unknown source.
  2. Ischemic Dilated Cardiomyopathy: Due to coronary artery disease, where there is a decreased blood flow to the heart muscle, it happens.
  3. Inflammatory Dilated Cardiomyopathy: This kind is connected to myocarditis or other inflammatory cardiac disorders.
  4. Genetic Dilated Cardiomyopathy: Specific gene mutations inherited from the parents are the cause.
  5. Alcoholic Dilated Cardiomyopathy: Alcoholism destroys the heart muscle over time, causing dilated cardiomyopathy.
  6. Peripartum Dilated Cardiomyopathy: It happens towards the end of pregnancy or soon after delivery, and it frequently resolves on its own over time.

Stages Dilated Cardiomyopathy

Dilated Cardiomyopathy can progress through four stages:

Stage 1: There are no symptoms or physical activity restrictions.

Stage 2: Mild symptoms and minimal restrictions when engaging in physical activity.

Stage 3: Observable signs and mild restrictions when exercising.

Stage 4: Significant limits, severe symptoms even when at rest, and a low quality of life.

Signs and Symptoms of Dilated Cardiomyopathy

  • Common signs and symptoms of Dilated Cardiomyopathy include:
  • Fatigue and weakness
  • Shortness of breath, especially during exertion or lying flat
  • Swelling (edema) in the legs, ankles, feet, or abdomen
  • Rapid or irregular heartbeat
  • Chest pain or discomfort
  • Dizziness or lightheadedness
  • Fainting or loss of consciousness (in advanced stages)

Diagnostic Criteria and Investigations:

The following diagnostic techniques and tests are frequently used to determine whether someone has dilated cardiomyopathy:

  • Physical examination: evaluating the symptoms, hearing the heartbeat, and examining the fluid retention.
  • Echocardiogram: Using ultrasound to assess the size, shape, and pumping efficiency of the heart.
  • Electrocardiogram (ECG): The heart's electrical activity is recorded, and any anomalies are found.
  • Cardiac MRI: gives clear photos of the heart so that you may evaluate its composition and operation.
  • Blood tests: biomarker research, including specialised genetic testing, if a hereditary cause is thought to be involved.
  • Coronary angiography: checking the heart's blood arteries to rule out coronary artery disease.

Treatment Options:

The goal of the Dilated Cardiomyopathy treatment programme is to control symptoms, limit the disease's course, and avert consequences. The therapy strategy can involve:

  1. Medications: Drugs prescribed for treating symptoms, regulating blood pressure, reducing fluid retention, and enhancing heart function.
  2. Lifestyle modifications: Establishing a heart-healthy lifestyle that consists of a balanced diet, frequent exercise, maintaining a healthy weight, and abstaining from alcohol and other drugs.
  3. Implantable devices: Pacemakers or implantable cardioverter-defibrillators (ICDs) may be suggested in specific circumstances to control heart rhythm and prevent unexpected cardiac arrest.
  4. Surgical interventions: Heart transplantation may be an option in severe situations or if medications and devices are unable to improve heart function.
  5. Cardiac rehabilitation: a planned programme to enhance general heart health and quality of life that includes supervised exercise, education, and counselling.

Preventions of Dilated Cardiomyopathy (DCM)

Adopting a healthy lifestyle and treating underlying diseases that may lead to the development of Dilated Cardiomyopathy (DCM) are two ways to prevent it. While Dilated Cardiomyopathy (DCM) may not always be preventable, the following steps can significantly lower the risk:

  1. Regular exercise: Maintain a healthy weight, enhance cardiovascular fitness, and advance general heart health by engaging in regular physical activity. Find out from a healthcare professional what kind and at what intensity of exercise is best for you.
  2. Heart-healthy diet: Maintain a nutritious diet that is balanced and full of fruits, vegetables, whole grains, lean meats, and good fats. Reduce your consumption of processed meals, sweet drinks, and saturated and trans fats. If you have high blood pressure or fluid retention, think about a low-sodium diet.
  3. Avoid alcohol and substance abuse: A type of Dilated Cardiomyopathy (DCM) called alcoholic cardiomyopathy can result from excessive alcohol use. Limit your alcohol consumption or don't drink at all. Stay away from illegal drugs as well, especially those that have negative effects on the heart.
  4. Manage chronic conditions: Manage underlying medical disorders such diabetes, high blood pressure, and autoimmune diseases that may be a factor in Dilated Cardiomyopathy (DCM). Take prescription drugs as instructed, adhere to the recommended course of therapy, and visit your healthcare practitioner on a regular basis.
  5. Genetic counseling and testing: Consider genetic counselling and testing if you have a family history of Dilated Cardiomyopathy (DCM) or believe there may be a genetic component. Making educated choices regarding family planning and early intervention can be facilitated by being aware of your genetic risk.
  6. Seek prompt medical attention: Seek immediate medical assistance if you have any heart-related symptoms, such as palpitations, shortness of breath, or chest pain. Early diagnosis and prompt treatment of cardiac problems can stop or slow the development of Dilated Cardiomyopathy (DCM).
  7. Manage stress: Chronic Heart health can be significantly impacted by stress. Adopt stress-reduction strategies including exercise, yoga, meditation, or hobby-based stress reduction to lower stress levels and enhance general wellbeing.
  8. Follow prescribed medications: Follow your doctor's prescription recommendations carefully if you have a heart ailment or other risk factors for it. These drugs could ease your symptoms, regulate your blood pressure, or lessen the strain on your heart.

It's crucial to remember that while these precautions can lower the likelihood of getting Dilated Cardiomyopathy (DCM), they cannot completely ensure prevention. Idiopathic or unidentified reasons may be present in some Dilated Cardiomyopathy (DCM) cases. To successfully monitor your heart health and treat any underlying issues, regular checkups and open contact with your doctor are crucial.

Conclusion:

A complex cardiac ailment called dilated cardiomyopathy causes the heart muscle to expand and weaken, which reduces its ability to pump blood and may cause difficulties. For people with Dilated Cardiomyopathy (DCM), prompt diagnosis, effective treatment, and lifestyle changes can greatly improve outcomes and quality of life. It is imperative to get medical advice from a specialist if you have any symptoms or worries about your heart health in order to receive an accurate assessment and recommendations.

 

Dr.Muhammad Arsalan Khan
MBBS, DHHM, MSc (D & E)
CCD-BMJ-AKU-RCP (London)

Congenital Heart Defects

 

Congenital Heart Defects

 

Introduction:

Heart disorders that develop before birth are known as congenital heart defects (CHDs). These conditions can have an impact on the heart's anatomy, function, or both at the time of a baby's birth. The most frequent birth defects, affecting one in every hundred infants, are congenital heart defects (CHDs). We will examine congenital heart defects in this blog, including their definition, causes, types, stages, symptoms, diagnostic standards, investigations, and available treatments..

Definition:

Congenital heart defects refer to structural problems in the heart that are present at birth. These abnormalities can affect the heart's walls, valves, blood vessels, or the electrical system that controls the heartbeat. Some defects are relatively minor and may not require treatment, while others can be life-threatening and need immediate medical intervention.

Causes:

Congenital heart defects frequently have uncertain specific aetiology. Congenital heart defects (CHDs) can, nevertheless, be more likely to occur in a baby if certain risk factors are present. These risk factors include genetics, maternal health issues (such diabetes or obesity), alcohol and drug addiction by the mother, the use of specific drugs during pregnancy, and exposure to viruses or toxins..

Types of Congenital Heart Defects:

There are several types of congenital heart defects, including:

  1. Septal Defects: The septum, or space between the heart chambers, has holes as a result of these anomalies. Atrial septal defect (ASD) and ventricular septal defect (VSD) are two examples.
  2. Valve Defects: The heart valves, which regulate blood flow inside the heart, are impacted by these flaws. This group includes conditions like mitral valve prolapse, pulmonary valve stenosis, and aortic stenosis.
  3. Cyanotic Heart Defects: These flaws result in less oxygen in the blood, which gives the skin and lips a bluish tinge. Tetralogy of Fallot, transposition of the major arteries, and truncus arteriosus are a few examples.
  4. Obstructive Defects: These flaws prevent blood from flowing normally via the heart or blood arteries. Examples of obstructive defects include pulmonary atresia and aortic Coarctation.

Signs & Symptoms:

The signs and symptoms of congenital heart defects vary depending on the type and severity of the defect. Some common indications include:

  • Cyanosis (bluish tint in the skin, lips, and nails)
  • Rapid breathing or shortness of breath
  • Poor weight gain and growth in infants
  • Fatigue and easy tiring during physical activity
  • Legs, the stomach, or the area around the eyes swelling
  • Abnormal heart rhythms
  • Recurrent respiratory infections

Diagnostic Criteria and Investigations:

To diagnose congenital heart defects, doctors may perform several tests and examinations, including:

  1. Physical Examination: Using a stethoscope, the doctor listens to the heart and lungs to hear any unusual heartbeats or murmurs.
  2. Echocardiogram: This ultrasound-based examination enables medical professionals to see the anatomy and operation of the heart, allowing them to spot specific problems.
  3. Electrocardiogram (ECG): This examination records the heart's electrical activity and looks for any unusual rhythms or patterns.
  4. Chest X-ray: X-ray images of the chest can provide information about the size, shape, and overall condition of the heart.

Treatment Options:

The type and severity of congenital heart abnormalities determine the appropriate course of treatment. Some common treatment options include:

  1. Medications: Certain medications can help manage symptoms or improve heart function in mild cases.
  2. Catheter Procedures: Less invasive procedures, such as cardiac catheterization, can be used to repair certain defects using thin tubes (catheters) inserted through blood vessels.
  3. Surgery: For more complex problems, open-heart surgery can be required. cardiac valves, holes, and cardiac components can all be repaired or replaced by surgeons as necessary.
  4. Heart Transplant: A heart transplant may be considered in extreme circumstances if the heart cannot be healed.

Preventions of Congenital Heart Defects

Even while many occurrences of congenital heart problems have no known origin, it may not always be possible to completely prevent them. However, some actions can help lower the chance of congenital heart abnormalities or enhance results. Here are some precautions to take:

  1. Preconception Care: It's crucial to look after your health in advance if you intend to get pregnant. Make an appointment with your doctor before becoming pregnant to go over any existing medical issues, prescription drugs, and lifestyle choices that may raise the possibility of congenital heart problems. Your doctor may provide required recommendations for immunizations, treat ongoing diseases, and offer advice on leading a healthy lifestyle.
  2. Prenatal Care: In order to keep track of the baby's health and development, regular prenatal care is essential. Attend all prenatal checkups as planned since your doctor will order a number of tests and screenings to look for any potential hazards. Early diagnosis of some illnesses can aid in their proper management and lower the chance of congenital heart abnormalities, such as diabetes or infections.
  3. Manage Chronic Working closely with your healthcare practitioner will help you manage any pre-existing medical disorders, such as diabetes, high blood pressure, or epilepsy, during pregnancy. Congenital cardiac abnormalities can be reduced with proper chronic disease care.
  4. Avoid Harmful Substances: Congenital cardiac abnormalities can be made more likely by a few drugs. Smoking, drinking, and using illegal substances must all be avoided while pregnant. These drugs may have a detrimental effect on fetal development and raise the risk of heart problems and other birth disorders.
  5. Genetic Counseling: Consider obtaining genetic counselling if you have a family history of congenital heart abnormalities or if you have ever had a child with a heart defect. A genetic counsellor can evaluate the likelihood of recurrence and offer important details regarding the likelihood of having a child with a congenital heart problem. If necessary, they can also go over the possibilities for genetic testing.
  6. Maintain a Healthy Lifestyle: Consume a diet that is well-balanced and full of vital nutrients, such as folic acid. It has been demonstrated that getting enough folic acid before conception and in the first trimester of pregnancy lowers the risk of developing several congenital heart abnormalities. Regularly exercise (with your doctor's consent) and keep your weight in a healthy range.
  7. Avoid Exposure to Infections: Congenital cardiac abnormalities are more likely to occur in some cases of infections during pregnancy. Practice good hygiene, frequently wash your hands, and avoid close contact with people who are contagious in order to prevent exposure to infections.

Remember, while these precautions can help lower the risk, they cannot absolutely guarantee that congenital cardiac abnormalities won't develop. It is always advisable to speak with your healthcare practitioner for specific advice and recommendations if you have worries or questions regarding your unique situation.

Conclusion:

Congenital heart defects are frequent birth disorders that alter the heart's composition and operation. Numerous variables can raise the risk even though the reasons of these problems are frequently unknown. Early detection through physical exams and diagnostic procedures is essential for prompt action and the right kind of care. With improvements in surgical methods and medical technology, many children with congenital heart abnormalities can now live happy, meaningful lives with the right support and care.

 

Dr.Muhammad Arsalan Khan
MBBS, DHHM, MSc (D & E)
CCD-BMJ-AKU-RCP (London)

Diabetes Milletus, Its Complications and Preventions

 

Diabetes Milletus 

Introduction:

Millions of individuals throughout the world suffer with diabetes, also known as diabetes mellitus, which is a chronic metabolic illness. It happens when the body is unable to properly control blood glucose levels. In-depth information about diabetes mellitus, including its definition, causes, types, stages, symptoms, diagnostic standards, research, and treatment choices, will be provided in this blog.

Definition of Diabetes Mellitus:

Diabetes Mellitus is a condition characterized by high blood sugar levels resulting from inadequate insulin production, impaired insulin action, or both. Insulin is a hormone produced by the pancreas that regulates the absorption and utilization of glucose in the body.

Causes of Diabetes Mellitus:

The emergence of diabetes mellitus is influenced by a number of factors, including:

In Type 1 Diabetes: This is an autoimmune disease in which the immune system unintentionally targets and kills the pancreatic cells that make insulin.

In Type 2 Diabetes: This kind often consists of both decreased insulin production and insulin resistance (cells that are less sensitive to insulin).

In Gestational Diabetes: This condition develops during pregnancy as a result of hormonal changes that impair insulin function and raise blood sugar levels.

Various drugs, endocrine abnormalities, genetic illnesses, pancreatic diseases, and other less frequent reasons are also possible.

Types of Diabetes Mellitus:

  1. Type 1 Diabetes: This type requires lifelong insulin therapy since the pancreas generates little or no insulin. This type is typically discovered in infancy or adolescence.
  2. Type 2 Diabetes: This kind makes up the majority of cases of diabetes and is typically brought on by lifestyle choices like obesity, inactivity, and poor eating patterns.
  3. Gestational Diabetes, which normally goes away after childbirth and develops throughout pregnancy. However, women who have gestational diabetes are more likely to go on to acquire type 2 diabetes in the future.

Stages of Diabetes Mellitus:

Diabetes mellitus can progress through various stages:

  1. Pre-diabetes: Blood sugar levels are above average but not high enough to be classified as diabetes. Without treatment, type 2 diabetes can develop from pre-diabetes.
  2. Early-stage diabetes: Although there are elevated blood sugar levels at this stage, there may be minimal or no symptoms.
  3. Advanced-stage diabetes: If blood sugar levels are not controlled, symptoms worsen and blood sugar levels stay continuously high.

Signs & Symptoms of Diabetes Mellitus:

Common signs and symptoms of diabetes mellitus include:

  • Increased thirst and frequent urination
  • Unexplained weight loss or weight gain
  • Fatigue and weakness
  • Blurred vision
  • Slow wound healing
  • Recurring infections, particularly urinary and skin infections

Types of complications of diabetes mellitus

Numerous problems that impact numerous human organs and systems might result from diabetes mellitus. There are two basic categories of problems:

  1. Acute Complications:

  • Diabetic Ketoacidosis (DKA): People with type 1 diabetes are more likely to experience this potentially fatal disease when there is a severe insulin shortage. It causes a buildup of ketones in the blood, which makes the environment more acidic.
  • Hyperosmolar Hyperglycemic State (HHS): People with type 2 diabetes are frequently affected by this ailment, which is typically brought on by persistently high blood sugar levels. High blood osmolality and severe dehydration are the results.

2. Chronic Complications:

  • Cardiovascular Complications: This covers peripheral artery disease, heart attack, coronary artery disease, and stroke.
  • Neuropathy: Peripheral neuropathy (affects the feet and legs), autonomic neuropathy (affects internal organs and automatic activities), and focal neuropathy (affects specific nerves, frequently producing acute pain or paralysis) can all result from diabetes-related nerve damage.
  • Nephropathy: It is a chronic disorder that can result in kidney failure and is also referred to as diabetic kidney disease.
  • Retinopathy: Diabetic retinopathy, which can damage retinal blood vessels as a result of diabetes and cause blindness, can impair vision.
  • Foot Complications: Diabetes can increase the risk of foot ulcers, infections, and amputation by causing poor circulation and nerve damage in the feet.
  • Skin Complications: Dryness, itching, bacterial and fungal infections, and sluggish wound healing are among side effects of diabetes that can damage the skin.
  • Sexual Dysfunction: Diabetes can be a factor in both male and female sexual dysfunction, including erectile dysfunction in males and decreased arousal and lubrication in women.
  • Dental Complications: Diabetes can increase the risk of oral health problems such tooth decay and gum disease.
  • Gastroparesis: Due to nerve injury, this illness results in a delayed stomach emptying, which causes digestive issues.
  • Increased Susceptibility to Infections: Diabetes can impair immune function, increasing vulnerability to infections, including skin, fungal, and urinary tract infections.

It's crucial to remember that not everyone with diabetes will develop every one of these issues. Complication risk and severity might vary depending on things including blood sugar control, how long a person has had diabetes, general health, and lifestyle choices. Effectively controlling diabetes and upholding a healthy lifestyle can help lower the risk and postpone the onset of these problems. Diabetes-related problems must be prevented and managed through proactive blood pressure, cholesterol, and blood sugar management.

 

Diagnostic Criteria for Diabetes Mellitus:

The following criteria are used to determine a diabetes mellitus diagnosis:

  1. Fasting Plasma Glucose (FPG) Test: a blood test that examines blood glucose levels after an overnight fast.
  2. Oral Glucose Tolerance Test (OGTT): In this test, blood glucose levels are measured both before and after eating a beverage high in glucose.
  3. Glycated Hemoglobin (A1C) Test: An average blood glucose level over the previous few months is provided by this test.

Investigations for Diabetes Mellitus:

To evaluate the general state of health and diabetes-related problems, additional research might be done, including:

  • Lipid profile: to assess triglyceride and cholesterol levels.
  • Kidney function tests: evaluating kidney health and identifying any harm.
  • Eye examination: to identify any diabetic retinopathy or other issues relating to the eyes.

Treatment of Diabetes Mellitus:

The goal of diabetes treatment is to control blood sugar levels and avoid complications. Typically, it entails:

  1. Lifestyle Modifications: A balanced diet, consistent exercise, weight management, and stress management are all part of this.
  2. Oral Medications: Oral medicines may be administered for people with type 2 diabetes to improve insulin action or boost insulin synthesis.
  3. Insulin Therapy: Some people with type 2 diabetes and those with type 1 may need to use an insulin pump or receive insulin injections.
  4. Continuous Glucose Monitoring (CGM): Real-time glucose readings from Continuous Glucose Monitoring (CGM) devices enable people to successfully monitor and control their blood sugar levels.

Preventions Of Diabetes mellitus

A combination of risk factor control and lifestyle changes can prevent diabetes mellitus. While some forms of diabetes, such as Type 1 diabetes, cannot be prevented, practising the following techniques can frequently delay or prevent Type 2 diabetes:

Healthy Eating:

  • Pick a diet that is well-balanced and full of fresh produce, whole grains, lean meats, and healthy fats.
  • Limit your intake of processed foods, foods heavy in saturated and trans fats, and sugary foods and drinks.
  • Limit your portion sizes and eat mindfully.

Regular Physical Activity:

  • Regularly work out, aiming for 150 minutes or more of aerobic activity at a moderate intensity per week.
  • Include weight-lifting activities to increase your muscular mass.
  • Integrate movement into daily activities to stay active all day long.

Weight Management:

  • By reaching and keeping a Body Mass Index (BMI) within the normal range (18.5 – 24.0), one can maintain a healthy body weight.
  • If you are overweight or obese, try to lose weight gradually by reducing your calorie intake, getting more exercise, and altering your behaviour..

Avoid Sedentary Lifestyle:

  • Limit sedentary activities like extended periods of sitting or screen usage.
  • Every 30 minutes, take a break from sitting and engage in some light exercise.

Blood Pressure Management:

  • Regularly check your blood pressure and make an effort to keep it within a healthy range (normally less than 120/80 mmHg).
  • Reduce alcohol consumption, eat low in salt, and get regular exercise to control blood pressure.

Healthy Blood Lipid Levels:

  • Keep an eye on your triglyceride and cholesterol levels in the blood.
  • Eat a diet that is high in unsaturated fats and low in saturated and trans fats.
  • To control lipid levels, exercise frequently and keep a healthy weight.

Avoid Tobacco Use:

  • Use no tobacco products or smoke.
  • If you are already a smoker, seek out assistance and tools to stop.

Moderate Alcohol Consumption:

  • Drink alcohol sparingly if you do.
  • Limit your alcohol consumption to moderate levels (one drink for women and two for males per day).

Regular Health Check-ups:

  • Plan routine medical exams to keep an eye on your blood pressure, blood sugar levels, and general wellness.
  • Observe your doctor's recommendations for diabetes prevention and screening.

Stress Management:

  • Take up stress-reduction practices like mindfulness, meditation, yoga, or relax-promoting pastimes and occupations.

Although these preventive actions can dramatically lower the risk of Type 2 diabetes, some people may still get the disease owing to a genetic predisposition or other uncontrollable circumstances. To receive individualised advise and perform risk assessment, regular medical examinations and meetings with healthcare specialists are needed.

Conclusion:

Diabetes mellitus is a chronic disease that needs constant attention. For people with diabetes and medical experts, it's critical to comprehend the reasons, varieties, phases, symptoms, diagnostic standards, tests, and available treatments. People with diabetes can live long, productive lives and reduce their risk of complications by managing their illness properly and taking a proactive attitude.

 

Dr.Muhammad Arsalan Khan
MBBS, DHHM, 
MSc (Diabetes & Endocrinology)
CCD-BMJ-AKU-RCP (London)

Rheumatic Heart Disease (RHD)

  Rheumatic Heart Disease (RHD)   Introduction: The dangerous disorder known as rheumatic heart disease (RHD), which affects the hear...